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What is the best way to deal with milk soy protein imbalance (MSPI)?

My baby is having a lot of discomfort all through out the day and night.

She is very gassy and grunts, groans and crys out often. She does not sleep unless you are up and moving around with her. We went to the pediatrician and she has microscopic blood in her stools.

I have been off of milk and soy for two weeks now with little improvement. What are the chances it isn't out of my system yet? I am willing to give it another week if it definitely takes 3 weeks to get out of my system. But I am saddened by how much pain my newborn is and I am ready to start formula. This is my second go around with a MSPI baby and the first was a breeze, this one is more difficult.


Kolene Moore | Other-provider

Kolene Moore

In "Breastfeeding and Human Lactation", by Jan Riordan, she states, “If the baby is truly sensitive to cow’s milk protein or another component of cow’s milk, it may take several days to weeks for the offending substance to be cleared from the baby’s body.”

Also research has shown that MSPI and GERD (reflux) go hand in hand and I am not sure if that could be adding to your daughter’s discomfort also.

Some sources suggest an imbalance of foremilk and hindmilk can mimic MSPI.

Foremilk is the thinner milk - with a lower fat content - which is the first milk a baby receives from the breast. This milk is richer in lactose since there is less fat content.

Hindmilk is the creamier, higher-fat milk which follows the foremilk. A mother with an overabundance of milk may have a higher quanity of foremilk, and some sources suggest that when milk production is high, baby may fill up on foremilk and then have difficulty digesting the lactose that is not balanced by fat. This is known as foremilk/hindmilk imbalance or oversupply.

It is always good to visit with mom about her supply and make sure it is not an oversupply issues or overfeeding issue. Hope this is helpful!

You can read more about breastfeeding issues in this section from ParentSavvy.

Read more answers by Dr. Moore